СИНДРОМ ЕНТЕРАЛЬНОЇ НЕДОСТАТНОСТІ У ХІРУРГІЧНИХ  ХВОРИХ: ОБ’ЄКТИВНА РЕАЛЬНІСТЬ ЧИ СИМПТОМ ХВОРОБИ?

Валерій  Бойко; Віктор  Польовий; Руслан Салютін; Олександр  Плегуца; Юрій Соловей; Микола Романовський

doi:10.24061/1727-0847.21.4.2022.46

Автор(и)

Валерій Бойко
Віктор Польовий
Руслан Салютін
Олександр Плегуца
Юрій Соловей
Микола Романовський

DOI:

https://doi.org/10.24061/1727-0847.21.4.2022.46

Ключові слова:

ентеральна недостатність; тонка кишка; ендотоксикоз

Анотація

Гострі хірургічні захворювання і травма в деяких випадках супроводжуються розвитком синдрому ентеральної недостатності, яка взаємообтяжує перебіг основного захворювання й збільшує летальність.
Метою цього наукового огляду є зосередження уваги клініцистів на появі синдрому ентеральної недостатності у перебігу гострої хірургічної патології й травматичної хвороби, яка потребує застосування індивідуалізованих лікувальних заходів.
Результати. При гострій хірургічній патології і травматичній хворобі виникає складна структурнофункціональна перебудова кишкового епітелію, яка порушує взаємозв’язки між клітинами кишкового епітелію, відторгнення епітеліоцитів і, як наслідок цього, – проникнення бактерій з просвіту кишки на власну пластинку, накопичення їх у стромі мікроворсинок і транслокацію у вільну очеревинну порожнину. Морфологічно це проявляється у вигляді ерозивно- виразкового дефекту або флегмонозного ентериту. У результаті формується синдром ендотоксикозу, який є причиною розвитку поліорганної недостатності в таких пацієнтів.
Висновок. Синдром ентеральної недостатності при гострій хірургічній патології органів очеревинної порожнини і травм є клінічно, лабораторно та морфологічно доведеним станом, який має періоди перебігу й відповідну клінічну симптоматику

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